WebFeb 28, 2014 · Cajanine, a constituent of Cajanaus cajan L., used in traditional Chinese medicine, is a promising drug candidate because of its broad range of bioactivities. However, the total synthesis of ... WebCajanine, a stilbenic component isolated from Cajanus cajan L., was identified as a potent HCV inhibitor by phenotypic screening in this work (EC50 = 3.17 ± 0.75 μM). The …
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Novel cajaninstilbene acid derivatives as antibacterial agents
WebJul 15, 2015 · In an effort to develop novel antibacterial agents, a variety of CSA derivatives have been designed and synthesized. As shown in Fig. 1, the drug design strategies include: (a) removal of the isoprenyl group of CSA, to obtain compounds 3a – 3k, 6a, 6c and 6f; (b) esterification of the carboxyl group, to synthesize 4a – 4k; (c) cleavage … WebCajanine can activate the cell cycle signal transduction pathway, thus inducing cells to enter the G1/S phase and accelerating cells entering the G2/M phase. This study can … WebCajanine preparation significantly reduced vascular permeability compared with the control: inhibition rate of cajanine preparations was 38.96%. Moreover, study on the effect of cajanine preparation on the pain threshold in mice showed that, compared with that of the mice prior to administration, both by drenching high- and low doses of ... standard test image