Dynein axonemal assembly factor 1
WebAdenomatous polyposis coli (APC) also known as deleted in polyposis 2.5 (DP2.5) is a protein that in humans is encoded by the APC gene. The APC protein is a negative regulator that controls beta-catenin concentrations and interacts with E-cadherin, which are involved in cell adhesion.Mutations in the APC gene may result in colorectal cancer.. APC is … WebJan 29, 2024 · In 3 probands with primary ciliary dyskinesia associated with combined inner and outer dynein arm defects (CILD13; 613193), Loges et al. (2009) identified …
Dynein axonemal assembly factor 1
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WebNX_Q8NEP3 - DNAAF1 - Dynein axonemal assembly factor 1 - Function. Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic …
WebMay 1, 2024 · The present study analyzes dynein axonemal assembly factor 1 (DNAAF1) and leucine-rich repeat-containing protein 50 (LRRC50), the corresponding encoded protein, in lower motor neurons in spinal cord of sALS postmortem samples and hSOD1-G93A … WebMar 26, 2013 · The DNAAF3 gene encodes a cytoplasmic axonemal dynein assembly factor with a key role in the assembly of both outer and inner dynein arms along the …
WebMar 1, 2024 · Figure 1. Organization of axonemal dynein motors. (A) Linear map of a generic ∼4500-residue dynein heavy chain.The amino-terminal region contains two conserved segments found in nearly all these motors: DHC_N1 is involved in heavy-chain assembly, whereas DHC_N2 represents the linker that traverses the plane of the AAA … WebJan 1, 2024 · Detailed study of axonemal and cytoplasmic dyneins has revealed several distinct classes of components, some of which are specifically found only in particular …
WebIPR027734 Dynein assembly factor 1, axonemal. IPR001611 Leucine-rich repeat. IPR032675 Leucine-rich repeat domain superfamily. Molecular Reagents less. All nucleic 8. cDNA 6. Primer pair 2. Microarray probesets 4. Other Accession IDs less. MGI:5505437 References more. Summaries. All 32. Developmental Gene Expression 4.
WebDescription: Homo sapiens dynein axonemal assembly factor 1 (DNAAF1), transcript variant 1, mRNA. (from RefSeq NM_178452) RefSeq Summary (NM_178452): The protein encoded by this gene is cilium-specific and is required for the stability of the ciliary architecture. It is involved in the regulation of microtubule-based cilia and actin-based … dashlane password manager loginWebFeb 26, 2024 · Andrés-Benito P, Povedano M, Torres P, Portero-Otín M, Ferrer I. Altered Dynein Axonemal Assembly Factor 1 Expression in C-Boutons in Bulbar and Spinal Cord Motor-Neurons in Sporadic Amyotrophic Lateral Sclerosis. J Neuropathol Exp Neurol. 2024;78: 416–425. pmid:30939186 . View Article PubMed/NCBI bite more than you can chewWebMar 4, 2012 · Primary ciliary dyskinesia (PCD) (MIM244400) affects 1 in every 15,000–30,000 live births and arises from ultrastructural defects that cause dysmotility of motile cilia in the respiratory ... dashlane password manager extensionWebSep 9, 2024 · dynein axonemal assembly factor 1, dynein assembly factor 1, axonemal, leucine-rich repeat-containing protein 50, outer row dynein assembly 7 … bite more than one can chewWebMar 4, 2012 · Abstract. Primary ciliary dyskinesia most often arises from loss of the dynein motors that power ciliary beating. Here we show that DNAAF3 (also known as PF22), a previously uncharacterized protein, is essential for the preassembly of dyneins into complexes before their transport into cilia. We identified loss-of-function mutations in the … bit emote twitchWebAug 1, 2024 · It is proposed that axonemal dynein factory formation in the cytoplasm may be a direct consequence of the sheer scale and complexity of the assembly process itself. Axonemal dyneins power the beating of motile cilia and flagella. These massive multimeric motor complexes are assembled in the cytoplasm, and subsequently trafficked to cilia … bite morphWebMar 21, 2024 · DNAAF1 (Dynein Axonemal Assembly Factor 1) is a Protein Coding gene. Diseases associated with DNAAF1 include Ciliary Dyskinesia, Primary, 13 and Primary … bite mouthpiece