mCherry-Parkin was a gift from Richard Youle (Addgene plasmid # 23956 ; http://n2t.net/addgene:23956 ; RRID:Addgene_23956) For your References section: Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. Narendra D, Tanaka A, Suen DF, Youle RJ. Web16 mrt. 2024 · FAT10 is, besides ubiquitin, the only ubiquitin-like modifier that directly guides its substrates to proteasomal degradation (Hipp et al., 2005).In fact, its intrinsic instability …
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WebPlasmid YFP-Parkin from Dr. Richard Youle's lab contains the insert Park2 and is published in J Cell Biol. 2008 Dec 1. 183(5):795-803. This plasmid is available through Addgene. … WebRapamycin-induced mitophagy was further elucidated by the translocation of mCherry Parkin to damaged mitochondria, which well correlates with our probe. Thus, PM-Mito … dianna agron as they made us
Endosomal Rab cycles regulate Parkin-mediated mitophagy
WebScale bar: 100 µm. c Mitochondrial Parkin in HEK293T expressing GFP-Parkin and either mCherry or PKI-mCherry, upon 1 h treatment with ISO, BAY-60 or their combination … http://www.biofeng.com/adjy/zhili/mCherry-Parkin.html Web线粒体自噬指细胞通过自噬机制选择性除去损伤或多余的线粒体。真核生物通过线粒体自噬调控线粒体质量,维持供能细胞器的功能。大量研究表明,帕金森病相关基因PINK1 … citibank and citimortgage