Phospho-sting-s366

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August undefined, 2024

WebPhospho-STING (Ser366) Antibody (PA5-117276) in WB Western blot analysis of extracts of THP-1 cells using Phospho-STING (Ser366) Polyclonal Antibody ( Product # PA5-117276 ). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Product Details Web(19781) Phospho-STING (Ser366) (D7C3S) Rabbit mAb Sign in or register to save this reagent to your favourites Supplier Cell Signaling Technology Host Rabbit Type Primary …

Phospho-STING-S365 Rabbit pAb (AP1199) - abclonal.com

WebStimulator of interferon genes (STING, TMEM173, MITA) is a transmembrane adaptor protein that is a critical component of the cellular innate immune response to pathogenic cytoplasmic DNA (1,2). STING is a ubiquitously expressed protein found predominantly in the ER (1). The enzyme cGAMP synthase (cGAS) produces the second messenger cyclic … WebPhosphorylated S366 is a docking site for IRF3 and is essential for the subsequent induction of Interferons (IFNs) ( 7, 8 ). Our previous work demonstrated that IRF3 binds to phosphorylated STING in the late endosomal compartment, where TBK1 phosphorylates and activates IRF3 ( 9 ). Additional proteins regulate the trafficking of STING. port arthur longshoreman attorney

Clathrin-associated AP-1 controls termination of STING signalling

Web靶标信息. STING is a 379 amino acid containing signaling protein that acts as an important component of innate immune signaling. This signaling protein is able to activate both NF … WebThe work by Lehmann et al classified TNBC into six subtypes in 2011. 5 Following this, two studies at our center further identified four transcriptome-based subtypes in TNBC: luminal androgen receptor (LAR), immunomodulatory (IM), basal-like immune-suppressed (BLIS), and mesenchymal-like (MES). 6 7 Furthermore, several reports have also … WebOct 1, 2024 · Phosphorylation of S358 enables TBK1 to bind STING. TBK1 then trans-phosphorylates S366 of neighboring STING complexes, allowing the recruitment ... [138]. Paradoxically, introduction of the phospho-mimic S366D also strongly reduces IRF3 dimerization and IFN I production [163, 164]. This may be due to clearance of … irish mule ingredients

Phospho-STING (Ser366) cellular HTRF kit Cisbio

Phospho-TMEM173/STING (Ser366) Antibody Affinity Biosciences

WebThe Phospho-STING (Ser366) assay uses 2 labeled antibodies: one with a donor fluorophore, the other one with an acceptor. The first antibody is selected for its specific … WebSep 23, 2024 · These findings provide insight into the mechanisms of PARPis in CAR-T cell therapy for RCC and suggest a promising adjuvant therapeutic strategy for CAR-T cell therapy in solid tumors. Supplementary Information The online version contains supplementary material available at 10.1186/s13045-021-01168-1. irish mule cocktailWebApr 6, 2024 · Binding of TBK1 to this motif promotes the phosphorylation of S366 in the STING tail 19, which subsequently recruits and promotes the phosphorylation of the transcription factor interferon... irish munchies

"WebJul 22, 2024 · Wu et al. demonstrate that HER2 recruits AKT1 to disrupt the STING signalosome, thereby suppressing damage-induced cellular senescence and STING … " - Phospho-sting-s366

Phospho-sting-s366

(19781) Phospho-STING (Ser366) (D7C3S) Rabbit mAb

WebFeb 15, 2024 · Here, we investigated the relationship between cGAS and phospho-STING (S366) protein expression levels in treatment-naïve LUAD tumors from the MD Anderson Cancer Center (MDACC) PROSPECT trial (n=120). As expected, phospho-STING (S366) protein levels were significantly correlated with cGAS protein levels (p=0.010) (Figure 1A). WebPhospho-STING (Ser366) (E9A9K) Rabbit mAb recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / Purification Monoclonal antibody is produced …

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WebPhospho-STING (Ser366) (E9A9K) Rabbit mAb from Cell Signaling Technology Supplier PageView Company Product Page Product Specs Company Info Reviews Back To Top … WebSTING (human) S366-p. 19781 : Phospho-STING (Ser366) (D7C3S) Rabbit mAb

WebThe antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns. Storage: … WebPhospho-TMEM173/STING (Ser366) Antibody Phospho-TMEM173/STING (Ser366) Antibody - #AF7416 (6) (9) WB IHC IF/ICC pElisa Cites 1 /9 Western blot analysis of extracts from UV treated RAW264. View similar products>> Related products Secondary Antibodies Loading Controls Blocking Peptides Cat.#S0018 Cat.#S0006 Cat.#S0008 Cat.#S0001 Cat.#S0013 …

WebPhospho-STING (Ser366) Antibody (PA5-105674) in ICC/IF. Immunofluorescent analysis of Phospho-STING (Ser366) in HepG2 cells … WebPhospho-STING (Ser366) Antibody (PA5-117276) in WB Western blot analysis of extracts of THP-1 cells using Phospho-STING (Ser366) Polyclonal Antibody ( Product # PA5-117276 …

WebAnti-Phospho-STING-S365 antibody produced in rabbit; find Sigma-Aldrich-SAB5701942 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich ... Anti-Phospho-TMEM173-S366 antibody produced in rabbit. View Price and Availability. ... Anti-phospho-Smad2/3 (pThr 8) antibody produced in rabbit. affinity ...

WebPhospho Sting S366, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 2 PubMed citations. ZERO BIAS - scores, article … irish mulled wine recipeWebMay 1, 2024 · (A) Heatmap shows correlation of phospho-STING (Ser_366) protein levels with cGAS and other immune-related proteins in the MD Anderson PROSPECT cohort, … port arthur maritime law attorneyWebProduct Description. This Cell Signaling Technology antibody is conjugated to Alexa Fluor ® 488 fluorescent dye and tested in-house for direct flow cytometric and immunofluorescent analysis in human cells. The antibody is expected to exhibit the same species cross-reactivity as the unconjugated Phospho-STING (Ser366) (D8K6H) Rabbit mAb #40818. irish mulligan stew recipeWebPhospho-STING (Ser366) two-plate assay protocol. The two-plate protocol involves culturing cells in a 96-well plate before lysis then transferring lysates to a low volume detection plate (either HTRF 384-lv or 96-lv plate) before adding HTRF Phospho-STING (Ser366) detection reagents. This protocol enables the cells' viability and confluence to ... irish murder casesPhospho-STING (Ser366) (D7C3S) Rabbit mAb recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser366 of human STING protein. Background port arthur memorial boys basketballWebWestern blot - Phospho-STING/TMEM173-S366 Rabbit pAb (AP1223) Western blot analysis of THP-1, using Phospho-STING/TMEM173-S366 … port arthur massacre bookWebPhospho-STING (Ser366) (E9A9K) Rabbit mAb from Cell Signaling Technology Supplier PageView Company Product Page Product Specs Company Info Reviews Back To Top Biocompare is the leading resource for up-to-date product information, product reviews, and new technologies for life scientists. About Biocompare About Biocompare port arthur medical clinic - set