Tīmeklisnifedipine + apixaban monitor bleeding s/sx; if also combined w/ strong CYP3A4 inhibitor, decr. apixaban dose by 50% or avoid combo if already on 2.5 mg bid; if also combined w/ moderate CYP3A4 inhibitor, consider decr. apixaban dose : combo may incr. apixaban levels, risk of bleeding, other adverse effects (P-gp-mediated transport … TīmeklisRaynaud’s phenomenon occurs in 90 % of patients with systemic sclerosis, 10–45 % of people with systemic lupus erythematosus, 33 % of people with Sjögren’s syndrome, …
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TīmeklisIt is a highly negatively inotropic calcium channel-blocker and it reduces cardiac output, slows the heart rate, and may impair atrioventricular conduction. It may precipitate heart failure, exacerbate conduction disorders, and cause hypotension at high doses and should not be used with beta-blockers. Constipation is the most common side-effect. Tīmeklis2001. gada 1. sept. · Results Clinical variables. Analysis of the symptom diaries showed that both fluoxetine and nifedipine produced a reduction in the severity and frequency of attacks of Raynaud's phenomenon (Figs 1 and 2 respectively).The reduction in attack severity was statistically significant with fluoxetine (P=0.0002) but not with … hse online shop bademode
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Tīmeklis2024. gada 4. nov. · Nifedipine reduces the frequency of painful attacks and the ischaemic ECG changes irrespective of the relative contribution from coronary artery … TīmeklisRaynaud's disease is a functional vasospastic disorder affecting the small arteries and arterioles of the extremities. It affects 3-20% of the adult population worldwide. Women are affected more often then men, especially younger ones. TīmeklisNifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood … hobby models pensacola