WebFeb 3, 2024 · The activation of PI3K induced by NS1 binding leads to the inhibition of apoptosis in influenza virus-infected cells, thus promoting viral replication [23,24,25]. ... The binding of NS1 to the coiled-coil domain of TRIM25 prevents the correct positioning of the PRYSPY domain of TRIM25 required for substrate ubiquitination, ... WebAnalysing mice that lack Tsc1 and the essential autophagy gene Rb1-inducible coiled-coil 1 (Rb1cc1, also called Fip200) in NSCs, we find that TSC-deficient cells require autophagy to maintain ...
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WebFrequent 39-Untranslated Region Mutation of the RB1- Inducible Coiled-Coil 1 Gene in Colon Tumors Bogdan C. Paun 1 , Yulan Cheng 1 , Barbara A. Leggett 3 , Joanne Young 4 , Stephen J. Meltzer 1,2 , Yuriko WebApr 12, 2024 · TRIM31, a member of the TRIM family, contains a N-terminal RING domain, a B-box domain, and two C-terminal coiled-coil (CC) domains . Especially, the RING domain perform as an E3 ubiquitin ligase and the deletion of RING domain can inhibit ubiquitination of TRIM31 itself or its substrate [ 34 ]. fish and chip restaurants near wakefield
Preparation of Mouse Monoclonal Antibody for RB1CC1 and Its
WebRB1-inducible coiled-coil 1 (RB1CC1) is a positive regulator for the retinoblastoma tumor suppressor (RB1) pathway, and is a suitable marker for evaluating the clinical course of breast cancer. We investigated whether RB1CC1 predicts the prognosis of … WebRB1-inducible coiled-coil 1 (RB1CC1) is a nuclear DNA-binding protein that can induce RB1 (retinoblastoma 1) expression. RB1CC1 is abundantly expressed in human musculoskeletal and cultured osteosarcoma cells. The present study analyzed the expression of RB1CC1 and RB1 in osteosarcoma cells and in m … WebAutophagy is an evolutionarily conserved cellular process in which intracellular components are eliminated via lysosomal degradation to supply nutrients for organelle biogenesis and metabolic homeostasis. Flavivirus infections underlie multiple human diseases and thus exert an immense burden on public health worldwide. Mounting evidence indicates that … campus footwear ipo